23. Marbois, B. N. and Clarke, C. F. (1996) "The COQ7 gene encodes a protein in Saccharomyces cerevisiae necessary for ubiquinone biosynthesis." J. Biol. Chem. 271, 2995-3004.

24. Shepherd, J.A., Poon, W.W., Myles, D.C. and Clarke, C. F. (1996) "The biosynthesis of ubiquinone: Synthesis and enzymatic modification of biosynthetic precursors." Tet. Lett. 37, 2395-2398.

25. Jonassen, T., Marbois, B. N., Kim, L., Chin, A., Xia, Y.-R., Lusis, A. J., and Clarke, C. F. (1996) "Isolation and sequencing of the rat COQ7 gene and the mapping of mouse COQ7 to chromosome 7." Arch. Biochem. Biophys. 330, 285-289.

26. Schultz, J.R., Ellerby, L.M., Gralla, E.B., Valentine, J.S. and Clarke, C. F. (1996) "Autoxidation of ubiquinol-6 is independent of superoxide dismutase." Biochemistry 35, 6595-6603.

27. Do., T. Q., Schultz, J. R. and Clarke, C. F. (1996) "Enhanced sensitivity of ubiquinone deficient mutants of Saccharomyces cerevisiae to products of autooxidized polyunsaturated fatty acids." Proc. Natl. Acad. Sci. U.S.A. 93, 7534-7539.

28. Hsu, A., Poon, W.W., Shepherd, J.A., Myles, D.C. and Clarke, C. F. (1996) "Complementation of coq3 mutant yeast by mitochondrial targeting of the E. coli UbiG polypeptide: Evidence that UbiG catalyzes both O-methylation steps in ubiquinone biosynthesis." Biochemistry 35, 9797-9806.

29. Poon, W.W., Do, T.Q., Marbois, B.N. and Clarke, C. F. (1997) "Sensitivity to treatment with polyunsaturated fatty acids is a general characteristic of the ubiquinone-deficient yeast coq mutants." Mol. Aspects Med. 18, s121-s127.

30. Lee, P. T., Hsu, A.Y., Ha, H. T. and Clarke, C. F. (1997) "A C-methyltransferase involved in ubiquinone biosynthesis: Isolation and identification of the Escherichia coli ubiE gene." J. Bacteriol. 179, 1748-1754.

31. Barkovich, R.J., Shtanko, A., Shepherd, J.A., Lee, P.T., Myles, D.C., Tzagoloff, A. and Clarke, C. F. (1997) "Characterization of the COQ5 gene from Saccharomyces cerevisiae: Evidence for a C-methyltransferase in ubiquinon biosynthesis." J. Biol. Chem. 272, 9182-9188.

32. Jonassen, T., Proft, M., Randez-Gil, F., Schultz, J.R., Marbois, B.N., Entian, K-D., and Clarke, C. F. (1998) "Yeast Clk-1 homologue (Coq7/Cat5): a mitochondrial protein in ubiquinone synthesis." J. Biol. Chem. 273, 3351-3357.

33. Santos-Ocana, C., Cordoba, F., Crane, F. L., Clarke, C. F. and Navas, P. (1998) "Coenzyme Q6 and iron reduction are responsible for the extracellular ascorbate stabilization at the plasma membrane of Saccharomyces cerevisiae." J. Biol. Chem. 273, 8099-8105.

34. Schultz, J. R. and Clarke, C. F. (1999) "Functional Roles of Ubiquinone" In Mitochondria, Oxidants, and Aging (Enrique Cadenas and Lester Packer, Eds.) Marcel Dekker, Inc., New York, pp. 95-118.

35. Santos-Ocana, C., Villalba, J. M., Cordoba, F., Padilla, S., Crane, F. L.,Clarke, C. F. and Navas, P. (1998) "Genetic evidence for coenzyme Q requirement in plasma membrane electron transport." J. Bioenerget. Biome 30:465-475.

36. Schultz, J. R. and Clarke, C. F. (1999) "Characterization of Saccharomyces cerevisiae ubiquinone-deficient mutants." BioFactors 9, 121-129.

37. Poon, W. W., Barkovich, R. J., Hsu, A.Y., Frankel, A., Lee, P. T., Shepherd, J.N., Myles, D.C. and Clarke, C.F. (1999) "Yeast and Rat Coq3 and E. coli UbiG catalyze both O-Methyltransferase steps in coenzyme Q biosynthesis." J. Biol. Chem. 274, 21665-21672

38. Vajo, Z., King, L. M., Jonassen, T., Ho, N., Munnich, A., Wilkin, D. J., Clarke, C. F., and Francomano, C. A. (1999) "Conservation of the C. elegans timing gene clk-1 from yeast to human: a gene required for ubiquinone biosynthesis with potential implications for aging." Mammalian Genome 10, 1000-1004.

39. Jonassen, T., and Clarke, C. F. (2000) "Isolation and functional expression of human COQ3, a gene encoding a methyltransferase required for ubiquinone synthesis." J. Biol. Chem. 275, 12381-12387.

40. Jonassen, T. and Clarke, C. F. (2000) "Genetic Analysis of Coenzyme Q Biosynthesis." in Coenzyme Q: From Molecular Mechanisms to Nutrition and Health, (Eds. Valerian E. Kagan and Peter J. Quinn) CRC Press, Boca Raton, FL, pp. 185-208.

41. Hsu, A. Y., Do, T. Q., Lee, P. T. and Clarke, C. F. (2000) "Genetic evidence for a multi-subunit complex in the O-methyltransferase steps of coenzyme Q biosynthesis." Biochim. Biophys. Acta 1484, 287-297.

42. Poon, W. W., Davis, D. E., Ha, H. T., Jonassen, T., Rather, P. N., and Clarke, C. F. (2000) "Identification of E. coli ubiB, a gene required for the first monooxygenase step in ubiquinone biosynthesis." J. Bacteriol. 182, 5139-5146.

43. Clarke C. F. (2000) "New Advances in Coenzyme Q Biosynthesis." Protoplasma, 213, 134-147.