Mg⁺² Localization on T_nA_n Tracts

N.V. Hud and J. Feigon: "Characterization of divalent cation localization in the minor groove of the A_nT_nand T_nA_n DNA sequence elements by ¹H NMR spectroscopy and manganese(II)", Biochemistry 41, 9900-9910 (2002).

Graphic representation of the relative line broadening exhibited by AH2, H1' and H4' protons of [d(CGT₄A₄CG)]₂, [d(GCGT₃A₃CGC)]₂ and [d(CGCGT₂A₂CGCG)]₂ as a function of MnCl₂ concentration. AH2, H1' and H4' protons are represented with Van der Waals radius spheres. DNA models shown are based upon idealized coordinates.