Feigon Lab

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Nucleic Acid Chime Demos

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Recent Publications:

C.A. Theimer, B.E. Jady, N. Chim, P. Richard, K.E. Breece, T. Kiss, and J. Feigon: “Structural and functional characterization of human telomerase RNA processing and Cajal Body localization signals” Molecular Cell 27, 869-881 (2007) [abstract]

 

K. Januszyk, P.W. Li, V. Villareal, D. Branciforte, H. Wu, Y. Xie, J. Feigon, J.A. Loo, S.L. Martin, and R.T. Clubb: "Identification and solution structure of a highly conserved C-terminal domain required for the retrotransposition of Long Interspersed Nuclear Element-1" J. Biol. Chem. 282, 24893-24904(2007) [abstract]

 

H. Wu and J. Feigon: "H/ACA small nucleolar RNA pseudouridylation pockets bind substrate RNA to form three-way junctions that position the target U for modification" PNAS 104, 6655-6660 (2007). [abstract]

 

R.J. Richards, H. Wu, L. Trantirek, C.M. O'Connor, k. Collins, and J. Feigon: "Structural study of elements of Tetrahymena telomerase RNA stem-loop IV domain important for function" RNA 12, 1475-1485 (2006). [abstract]

 

C.A. Theimer and J. Feigon: "Structure and function of telomerase RNA", Curr. Opin. Struct. Biol. 16, 307-318 (2006). [abstract]

 

R.J. Richards, C.A. Theimer, L.D. Finger, and J. Feigon: "Structure of the Tetrahymena thermophila telomerase RNA helix II template boundary element", Nucleic Acids Res. 34, 816-825 (2006). [abstract]

 

M. Khanna, H. Wu, C. Johansson, M. Caizergues-Ferrer, and J. Feigon, "Structural study of the H/ACA snoRNP components Nop10p and the 3' hairpin of U65 snoRNA", RNA 12, 40-52 (2006) [abstract]

 

A.J. Dingley, R.D. Peterson, S. Grzesiek, and J. Feigon, "Characterization of the cation and temperature dependence of DNA quadruplex hydrogen bond properties using high-resolution NMR", J. Am. Chem. Soc. 127, 14466-72 (2005). [abstract]

 

A.K. Henras, M. Sam, S.L. Hiley, H. Wu, J. Feigon, T.R. Hughes, and G.F. Chanfreau: "Biochemical and genomic and analysis of substrate recognition by the double stranded RNA binding domain of yeast RNase III", RNA 11, 1225-1237 (2005). [abstract]

 

P.Z. Qin, J. Feigon, and W. Hubbell: "Site-directed spin labeling studies reveal a coupled mechanism in the formation of the GAAA tetraloop/receptor RNA tertiary interaction", J. Mol. Biol. 351, 1-8 (2005). [abstract]

 

H. Wu, L.D. Finger, J. Feigon: "Structure determination of Protein/RNA complexes by NMR", in Methods in Enzymol. (T.L. James, ed.) Academic Press, 394, 525-545 (2005). [abstract]

 

C.A. Theimer, C.A. Blois, and J. Feigon: "Structure of the human telomerase RNA pseudoknot reveals conserved tertiary interactions essential for function", Mol. Cell 17, 671-682 (2005). [abstract]

 

M. Kamionka and J. Feigon: "Structure of the XPC binding domain of hHR23A reveals hydrophobic patches for protein interaction", Protein Science, 13, 2370-2377 (2004). [abstract]

 

J. Feigon and C. Bustamante: “Nucleic acids – controlling biology and controlled by biophysics” Curr. Opin. Struct. Biol., 14, 333-334 (2004).

 

L.D. Finger, C. Johansson, B. Rinaldi, P. Bouvet, and J. Feigon "Contributions of the RBDs and linker domains and RNA structure to the specificity and affinity of the nucleolin RBD12/NRE interaction" Biochemistry, 43, 6937-6947 (2004). [abstract]

 

H. Wu, A. Henras, G. Chanfreau, and J. Feigon: “Structural basis for recognition of the AGNN tetraloop RNA fold by the double-stranded RNA binding domain of Rnt1p Rnase III”, Proc. Natl. Acad. Sci. USA, 101, 8307-8312 (2004). [abstract]

 

C. Johansson, L.D. Finger, L. Trantirek, T.D. Mueller, S. Kim, I.A. Laird-Offringa, and J. Feigon: “Solution structure of the complex formed by the two N-terminal RNA-binding domains of nucleolin and a pre-rRNA target”, J. Mol. Biol., 337, 799-816 (2004). [abstract]

 

T.D. Mueller, M. Kamionka, and J. Feigon: “Specificity of the interaction between UBA domains and ubiquitin”, J. Biol. Chem., 279, 11926-11936 (2004). [abstract]

 

R. Stefl, H. Wu, S. Ravindranathan, V. Sklenár, and J. Feigon: “DNA A-tract bending in three dimensions: Solving the dA4T4 versus dT4A4 conundrum”, Proc. Natl. Acad. Sci. USA, 101, 1177-1182 (2004). [abstract]

 

R.D. Peterson, C.A. Theimer, H. Wu, and J. Feigon: “New Applications of 2D Filtered/Edited NOESY for Assignment and Structure Elucidation of RNA and RNA-Protein Complexes”, J. Biomol. NMR, 28, 59-67 (2004). [abstract]

 

C.A. Theimer, L.D, Finger, and J. Feigon: “YNMG tetraloop formation by a dyskeratosis congenita mutation in human telomerase RNA”, RNA, 9, 1446-1455 (2003). [abstract]

 

L.D. Finger, L. Trantirek, C. Johansson, and J. Feigon: “Solution structures of stem-loop RNAs that bind to the two N-terminal RNA-binding domains of nucleolin”, Nucleic Acids Res. 31, 6461-6472 (2003). [abstract]

 

T.M. Mueller and J. Feigon: “Structural determinants for the binding of ubiquitin-like domains to the proteasome”, EMBO J., 22, 4634-4645 (2003). [abstract]

 

P.Z. Qin, K. Hideg, J. Feigon, and W.L. Hubbell: "Monitoring RNA base structure and dynamics using site-directed spin labeling", Biochemistry, 42, 6772-6783 (2003). [abstract]

 

C.A. Theimer, L.D. Finger, L. Trantirek, and J. Feigon: "Mutations linked to dyskeratosis congenita cause dynamic changes in telomerase RNA structure", Proc. Natl. Acad. Sci. USA, 100, 449-454 (2003). [abstract]

 

Complete Publication List