Metal Binding Sites on Domain B
of the Hairpin Ribozyme

S.E. Butcher, F.H.-T. Allain, and J. Feigon: "Determination of metal ion binding sites within the hairpin ribozyme domains by NMR", Biochemistry 39, 2174-2182 (2000). [abstract]

Structure models of the metal binding sites on domain B. (A) Site 1, rotated to illustrate the five possible hydrogen bonds between the Mn(H₂0)₆²⁺ ion and the RNA. (B) Site 2, rotated to illustrate the four possible hydrogen binds between the Mn(H₂0)₆²⁺ ion and the RNA.