H/ACA U65 complex with RNA substrate

H. Wu and J. Feigon: "H/ACA small nucleolar RNA pseudouridylation pockets bind substrate RNA to form three-way junctions that position the target U for modification" PNAS 104, 6655-6660 (2007). [abstract]

PDB Code: 2P89

Stick and ribbon (left), surface representation (middle), and schematic (right) of the U65 complex with its substrate RNA, positioning the target U for pseudouridylation.